BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Research Seminars//NONSGML Events//EN CALSCALE:GREGORIAN X-ORIGINAL-URL:https://calendar.med.wustl.edu/calendar/list/ X-WR-CALDESC:Research Seminars - Events BEGIN:VEVENT UID:20250128T2009Z-1738094997.361-EO-32366-1@10.73.10.235 STATUS:CONFIRMED DTSTAMP:20260519T062407Z CREATED:20250128T200851Z LAST-MODIFIED:20250129T175151Z DTSTART;TZID=America/Chicago:20250206T120000 DTEND;TZID=America/Chicago:20250206T130000 SUMMARY: Genetics Seminar: Andrew Yoo\, PhD DESCRIPTION: Andrew Yoo\, PhD Talk Title: Neuronal reprogramming of human s omatic cells and modeling of late-onset neurodegeneration Host: Dr. Susan D utcher Abstract: Ectopic expression of brain-enriched microRNAs\, miR-9/9* and miR-124\, in non-neural somatic cells can induce robust chromatin recon figuration and cell fate conversion to neurons. Because of the nature of th is direct conversion\, the reprogrammed human […] X-ALT-DESC;FMTTYPE=text/html:

Andrew Yoo\, PhD

Talk Title: Neu ronal reprogramming of human somatic cells and modeling of late-onset neuro degeneration

Host: Dr. Susan Dutcher

Abstract: Ectopic exp ression of brain-enriched microRNAs\, miR-9/9* and miR-124\, in non-neural somatic cells can induce robust chromatin reconfiguration and cell fate con version to neurons. Because of the nature of this direct conversion\, the r eprogrammed human neurons capture many aspects of brain aging. I will discu ss our most updated understanding of the neuronal conversion process and ho w these reprogrammed human neurons are deployed to model late-onset neurode generation.

CATEGORIES:genetics,Seminars / Lectures LOCATION:Connor Auditorium\, Farrell Learning and Teaching Center GEO:38.635021;-90.263078 ORGANIZER;CN="Michelle":MAILTO:gibbsm@wustl.edu URL;VALUE=URI:https://calendar.med.wustl.edu/calendar/event/genetics-semina r-andrew-yoo-phd/ END:VEVENT BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:STANDARD TZOFFSETFROM:-0500 TZOFFSETTO:-0600 DTSTART:20241103T070000 TZNAME:CST END:STANDARD END:VTIMEZONE END:VCALENDAR