BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Research Seminars//NONSGML Events//EN CALSCALE:GREGORIAN X-ORIGINAL-URL:https://calendar.med.wustl.edu/calendar/list/ X-WR-CALDESC:Research Seminars - Events BEGIN:VEVENT UID:20240821T2116Z-1724274981.565-EO-31941-1@10.24.106.144 STATUS:CONFIRMED DTSTAMP:20260512T123908Z CREATED:20240821T211304Z LAST-MODIFIED:20240903T191232Z DTSTART;TZID=America/Chicago:20241010T120000 DTEND;TZID=America/Chicago:20241010T130000 SUMMARY: Genetics Seminar Series DESCRIPTION: Massively parallel reporter assays\, quantitative sequence-fun ction relationships\, and splice-modifying drugs Host: Dr. Mike White In pe rson: Connor Auditorium (FLTC) Abstract: My lab studies the biophysical mec hanisms of transcriptional regulation and alternative mRNA splicing. To do this we use massively parallel reporter assays and machine learning/AI meth ods to measure and mechanistically model the quantitative effects that […] X-ALT-DESC;FMTTYPE=text/html:

Massively parallel reporter assays\, quant itative sequence-function relationships\, and splice-modifying drugs

Host: Dr. Mike White

In person: Connor Auditorium (FLTC)

Abstra ct: My lab studies the biophysical mechanisms of transcriptional regulation and alternative mRNA splicing. To do this we use massively parallel report er assays and machine learning/AI methods to measure and mechanistically mo del the quantitative effects that mutations in regulatory sequences have on gene expression. I will provide an overview this research program\, focusi ng in particular on the tightly knit combination of experimental\, computat ional\, and mathematical work it involves.

CATEGORIES:Seminars / Lectures LOCATION:Connor Auditorium\, Farrell Learning and Teaching Center GEO:38.635021;-90.263078 ORGANIZER;CN="Michelle":MAILTO:gibbsm@wustl.edu URL;VALUE=URI:https://calendar.med.wustl.edu/calendar/event/genetics-semina r-series-19/ END:VEVENT BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:DAYLIGHT TZOFFSETFROM:-0600 TZOFFSETTO:-0500 DTSTART:20240310T080000 TZNAME:CDT END:DAYLIGHT END:VTIMEZONE END:VCALENDAR