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BEGIN:VEVENT
UID:20260112T2214Z-1768256068.1111-EO-32863-1@10.73.7.199
STATUS:CONFIRMED
DTSTAMP:20260713T181017Z
CREATED:20260112T220238Z
LAST-MODIFIED:20260218T193453Z
DTSTART;TZID=America/Chicago:20260226T120000
DTEND;TZID=America/Chicago:20260226T130000
SUMMARY: Genetics Seminar Series\, Dutcher Tenure Recognition Seminar: Guoy
 an Zhao\, PhD
DESCRIPTION: Guoyan Zhao\, PhD Associate Professor with Tenure Department o
 f Genetics\, WashU Medicine Talk Title: A Unified Framework for Elucidating
  Molecular Mechanisms of Disease and Evolution Abstract: Through comparativ
 e single-cell genomics data analysis\, we identified convergent molecular m
 echanisms of neurodegeneration across diseases\, brain regions\, and specie
 s in astrocytes\, microglia\, and neurons. We developed a unified framework
  […]
X-ALT-DESC;FMTTYPE=text/html: <h4>Guoyan Zhao\, PhD</h4><p>Associate Profes
 sor with Tenure</p><p>Department of Genetics\, WashU Medicine</p><p>Talk Ti
 tle: A Unified Framework for Elucidating Molecular Mechanisms of Disease an
 d Evolution</p><p>Abstract: Through comparative single-cell genomics data a
 nalysis\, we identified convergent molecular mechanisms of neurodegeneratio
 n across diseases\, brain regions\, and species in astrocytes\, microglia\,
  and neurons. We developed a unified framework for the accurate identificat
 ion of cis-regulatory sequences across vertebrate genomes and demonstrated 
 its power in detecting evolutionarily non-conserved enhancers\, annotating 
 regulatory sequences in non-model organisms\, and uncovering disease-causal
  variants and their underlying regulatory mechanisms.</p><p>Host: Dr. Susan
  Dutcher</p>
CATEGORIES:Seminars / Lectures
LOCATION:Moore Auditorium\, North Building\, 1st Floor
GEO:38.635205;-90.261861
ORGANIZER;CN="Michelle":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://calendar.med.wustl.edu/calendar/event/genetics-semina
 r-series-guoyan-zhao-phd/
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TZOFFSETFROM:-0500
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DTSTART:20251102T070000
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