Adam Wende, PhD
Associate Professor
Department of Pathology
The University of Alabama at Birmingham

Department of Genetics

Metabolic signaling in transcriptional control of heart failure

Hosted by: Dr. Peter Jin

In person only: Connor Auditorium (FLTC)

Abstract:  Cardiovascular diseases are the leading cause of death, and diabetes enhances susceptibility and severity of heart failure. Epidemiological studies support the hypothesis that poor glycemic control, even after corrected, impacts disease pathology. We will discuss evidence for glucose-mediated regulation of the transcriptional changes that are associated with pathological cardiac remodeling in this context.