Mapping and Modeling Transcriptional Regulatory Networks Hosted by:  Dr. Guoyan Zhao and Genetics students & postdocs In-person only:  Connor Auditorium (FLTC) Abstract: Transcription factor (TF) binding locations can be mapped using methods such as ChIP-Seq or Calling Cards and the functional targets of a TF can be identified by perturbing the TF and measuring changes in […]

Massively parallel reporter assays, quantitative sequence-function relationships, and splice-modifying drugs Host: Dr. Mike White In person: Connor Auditorium (FLTC) Abstract: My lab studies the biophysical mechanisms of transcriptional regulation and alternative mRNA splicing. To do this we use massively parallel reporter assays and machine learning/AI methods to measure and mechanistically model the quantitative effects that […]